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Levothyroxine Systematic (IUPAC) name 3,5,3',5'-Tetraiodo-L-thyronine Identifiers CAS number 51-48-9 ATC code H03AA01
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PubChem
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DrugBank APRD00235 Chemical data Formula C15H11I4NO4 Mol. mass 798. 86 (anhydrous) SMILES eMolecules & PubChem Synonyms O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Pharmacokinetic data Bioavailability ~100% Metabolism Mainly in liver, kidneys, brain and muscles Half life ca. 7 synthrid (in hyperthyroidism 3-4 days, in
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9-10 days) does soy affect taking synthroid Excretion Through feces and urine Therapeutic considerations Pregnancy cat. A(US)
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status ℞ Prescription only Routes Oral, Intravenous Levothyroxine, also L-thyroxine, mechanism of action of synthroid T4, or 3,5,3',5'-tetraiodo-L-thyronine, is a synthetic form of thyroxine (thyroid hormone). The natural hormone
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chemically in the L-form, as is the pharmaceutical agent. Dextrothyroxine syntnroid briefly saw research as an
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agent but was pulled due to cardiac side-effects. The EU has recently standardized the use synthroid 225 mg the International Nonproprietary Name "levothyroxine" for the drug. Common brand recommended dosage synthroid include Thyrax, Euthyrox, Levaxin, L-thyroxine and Eltroxin in Europe; synthroid substitute for soloxine in South Asia; Eutirox, Levoxyl and Synthroid in North America. There are also numerous
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versions. Contents synthroid and weight gain Uses 2 Dosage synthroid side affects synthroid 3 Adverse synthroid vs levothyroxin 4 Marketing and approvals endocrinology synthroid versus thyroxine
the United
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5 References 6 External links // Uses This medicine
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a hormone replacement usually given to patients with thyroid problems, specifically, hypothyroidism. It also
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been given to people who have goitre or an enlarged thyroid gland. Dosage and precautions Dosages vary according the age groups and the individual synthroid contradictions of the patient, body weight and compliance to the synthroid doses and diet. Maximum dosage may reach 400 mcg per day but that is rare. Monitoring of the patients condition
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adjustment what side effects does synthroid have the dosage is periodical and necessary. Levothyroxine is taken on an empty stomach approximately half an
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to side effects of thyroid drug synthroid hour before meals to maximize its absorption, often with water to ease swallowing and help the tablet dissolve for absorption. There are also foods and other substances that can interfere with absorption of thyroxine synnthroid Patients under treatment ought to avoid taking calcium synthroidd iron supplements within 4 hours, as well as soy products within 3 hours of the medication, as these can reduce absorption of the drug. Other substances that reduce absorption
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aluminium and magnesium containing antacids, simethicone or sucralfate, cholestyramine, colestipol, Kayexalate. Recently, it has been discovered that caffeine
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also interfere with the intestinal absorption of levothyroxine. Different substances cause other adverse effects that may be severe. Ketamine may cause hypertension and tachycardia and tricyclic and
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antidepressants increase its toxicity. On the synthroid and damiana hand Lithium can cause
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(but most often
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by affecting iodine metabolism of the thyroid itself
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thus inhibits synthetic levothyroxine as well. Adverse effects Synthetic levothyroxine can cause adverse effects
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as palpitations, nervousness, headache, insomnia, swelling of the legs and ankles, interactions with synthroid loss, and increased appetite. Allergies reactions to the drug are characterized by symptoms such as difficulty breathing, shortness of breath, or swelling of the face hyperthyroid tapazole and synthroid tongue. Acute overdose may cause fever, hypoglycemia, heart failure,
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and unrecognized adrenal
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Acute massive overdose may be life-threatening; treatment should be symptomatic and supportive. Massive overdose may require beta-blockers for increased sympathomimetic
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Studies have shown that using liothyronine in combination with levothyroxine
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not produce synergistic effects; other studies discourage the hyperthyroid tapazole and synthroid
of
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two medications concurrently. The side effects synthoid overdosing buy synthroid online without prescription 6 hours to 11 days after ingestion. Marketing and
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in the United States
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25 µg tablets Synthroid synnthroid the discontinuing synthroid prescribed brand of T4 in the United States. Synthroid
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marketed in 1955, but was not FDA approved at that time as it was "generally regarded safe". In the 1990s, in response to debate as to whether Synthroid was more effective than other levothyroxine preparations, (which ended up concluding that there was effects of stopping synthroid difference between Synthroid and generic brands) all levothyroxine preparations were
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to undergo the formal FDA approval
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Synthroid was approved by the FDA on 2002-07-24. References ^ Vaidya B, Pearce SH (2008). "Management
generic synthroid
hypothyroidism discontinuing synthroid adults". BMJ (Clinical
synthroiid
ed. ) 337: a801. PMID
